Table 3.
Univariate analysis of factors associated with mortality in patients with GNB.
| Surviving N = 806 |
Death N = 63 |
RR (95%CI) | P | |
|---|---|---|---|---|
| Demographics | ||||
| Male | 426 (52.9) | 32 (50.8) | 0.93 (0.58-1.49) | 0.43 |
| Age >65 y | 581 (72.2) | 54 (85.7) | 2.20 (1.11-4.39) | 0.01 |
| Comorbidity | ||||
| Diabetes mellitus | 130 (16.2) | 9 (14.3) | 0.87 (0.56-2.41) | 0.43 |
| Neoplasm | 74 (9.2) | 7 (11.1) | 1.2 (0.57-2.57) | 0.38 |
| Immunosuppression | 31 (3.9) | 6 (9.5) | 2.36 (1.08-5.11) | 0.046 |
| Liver cirrhosis | 41 (5.1) | 7 (11.1) | 2.13 (1.02-4.41) | 0.052 |
| Chronic renal failure | 45 (5.6) | 6 (9.5) | 1.68 (0.76-3.71) | 0.16 |
| Charlson index ≥3 | 129 (16) | 21 (33.3) | 2.4 (1.46-3.92) | 0.001 |
| Microorganism | ||||
| Escherichia coli | 664 (82.4) | 46 (73) | 0.61 (0.36-1.03) | 0.05 |
| Klebsiella spp. | 48 (6.0) | 5 (7.9) | 1.33(0.56-3.17) | 0.34 |
| Proteus spp. | 40 (5.0) | 4 (6.3) | 1.27 (0.48-3.34) | 0.4 |
| Salmonella spp. | 34 (4.2) | 5 (7.9) | 1.84 (0.78-4.32) | 0.14 |
| Enterobacter spp. | 19 (2.4) | 3 (4.8) | 1.93 (0.65-5.67) | 0.21 |
| Polymicrobial bacteremia | 56 (6.9) | 11 (17.5) | 2.56 (1.4-4.64) | 0.006 |
| Adequate empirical treatment | 610 (83.7) | 38 (70.4) | 0.5 (0.28-0.86) | 0.014 |
| Origin of infection | ||||
| Urinary | 466 (58.3) | 18 (29.0) | 0.32 (0.19-0.54) | <0.0001 |
| Biliary | 147 (18.4) | 10 (16.1) | 0.86 (0.45-1.66) | 0.4 |
| Unknown | 101 (12.6) | 15 (24.2) | 2.05 (1.19-3.54) | 0.013 |
| Intra-abdominal | 32 (4.09 | 5 (8.1) | 1.95 (0.83-4.58) | 0.12 |
| Pneumonia | 10 (1.3) | 6 (9.7) | 5.66 (2.86-11.18) | <0.001 |
| Presentation | ||||
| Septic Shock | 4 (0.5) | 5 (7.9) | 8.24 (4.37-15.54) | <0.0001 |
Data are no. (%) of patients. RR: Relative risk