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. 2010 Jul 29;6(7):e1000867. doi: 10.1371/journal.pcbi.1000867

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Wong et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The top (average log probability per predicted signal peptide for SCOP v1.75 α- and membrane protein class) and bottom (average log probability per predicted signal peptide for SMART version) histograms represent the false-positive and true-positive distributions for the SP predictions respectively. The total number of predicted signal peptides for SCOP α- and membrane proteins is 193 and 379 respectively, while the total number for SMART is 45. All except SM00817 Amelin (no available structure) were validated against their respective PDB entries.