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List of known Rb1-repressed genes identified as potential Tbx2 targets
| DNA replication/repair | Mitosis | Chromatin/epigenetic regulation |
|---|---|---|
| Lig1 | CyclinB1 | Dnmt1 |
| Mcm2 | Cdc2a | Np95* |
| Mcm6 | Plk | Ezh2 |
| Mcm7 | Prc1 | Hmgb2 |
| CyclinA2 | Bub1* | Asf1b |
| Top2a | ||
| PCNA | ||
| Rrm1 |
Boldface indicates genes that are targeted by ER-Tbx2(1-301) but not by the ER-Tbx2(1-301mt) protein, which does not bind Rb1. Asterisks mark genes that are not regulated by E2F.
