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. 2010 Jul 29;5(7):e11879. doi: 10.1371/journal.pone.0011879

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Hanin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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LoxP sites are composed of two 13 pb inverted sequences separated by an 8 pb spacer region which gives the orientation of the LoxP site [56]. The base indicated by * is deleted in the second loxP site of Lox2ΔG strain.