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. Author manuscript; available in PMC: 2011 Jul 21.
Published in final edited form as: J Am Chem Soc. 2010 Jul 21;132(28):9820–9825. doi: 10.1021/ja103010b

Figure 4.

Figure 4

The observed H/T (filled structures) and D/T (empty structures) KIEs plotted vs. fraction conversion as measured at 25 °C with 3 μM CH2H4folate. The different colors and shapes represent different independent experiments.