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. Author manuscript; available in PMC: 2011 Jul 21.
Published in final edited form as: Bioconjug Chem. 2010 Jul 21;21(7):1297–1304. doi: 10.1021/bc1000998

Figure 10.

Figure 10

Probe 1 targets bacterial infection and not sterile inflammation in immunocompetent mice (strain ICr). (top) Mice were treated with 10 nmol of probe 1 six hours after the left posterior leg was injected with ~108 CFU of S. aureus NRS11 [A], 50 µL of a 1 % λ-carrageenan solution [B], or 50 µL of a sterile saline solution [C]. The dorsal images were acquired at 12 hours post injection of probe. (bottom) Graph depicts the change in target-to-nontarget ratios (T/NT) obtained via ROI analyses of images. Error bars represent standard error of the mean. N = 3 for each group.