Table 2.
Low 53BP1 expression correlates with triple-negative status (Yale cohort)
| 53BP1 expression |
||||
|---|---|---|---|---|
| Features | Total (%) | Positive (%) | Negative (%) | p * |
| ER | ||||
| positive | 243 (55) | 239 (63) | 4 (6) | |
| negative | 200 (45) | 140 (37) | 60 (94) | <0.0001 |
| PR | ||||
| positive | 226 (51) | 222 (59) | 4 (6) | |
| negative | 217 (49) | 157 (41) | 60 (94) | <0.0001 |
| ERBB2/HER2 | ||||
| positive | 78 (18) | 77 (20) | 1 (2) | |
| negative | 366 (82) | 303 (80) | 63 (98) | <0.0001 |
| Triple-negative (TN) | ||||
| Not TN | 311 (70) | 305 (80) | 6 (10) | |
| TN | 132 (30) | 75 (20) | 57 (90) | <0.0001 |
Fisher’s exact test.