Table 1.
Baseline characteristics of patients with Plasmodium falciparum regarding seven treatment regimens, Colombia
| Characteristic | No. | Age (years) | Weight (kg) | Asexual parasites/μL | Gametocytes/μL | ||||
|---|---|---|---|---|---|---|---|---|---|
| P*50 | P(25–75) | P50 | P(25–75) | P50 | P(25–75) | P50 | P(25–75) | ||
| CQ and SP | 64 | 17.5 | 7.5–36.8 | 51.5 | 32.3–62.0 | 2,860 | 1,190–7,700 | 0 | 0–0 |
| AQ and SP | 91 | 21.0 | 14.0–30.8 | 57.6 | 42.4–63.6 | 4,860 | 2,280–12,330 | 0 | 0–0 |
| MQ and SP | 92 | 23.0 | 13.0–37.0 | 58.0 | 40.1–67.2 | 4,310 | 1,550–10,285 | 0 | 0–0 |
| AS and SP | 98 | 22.0 | 15.0–41.0 | 58.3 | 45.0–66.0 | 5,110 | 2,198–13,025 | 0 | 0–0 |
| AS and AQ | 52 | 30.0 | 15.5–38.0 | 59.0 | 46.4–70.0 | 7,120 | 2,750–17,095 | 0 | 0–0 |
| AS and MQ | 25 | 20.0 | 14.0–41.1 | 50.3 | 40.5–62.5 | 3,280 | 1,220–7,140 | 0 | 0–20 |
| AS, MQ, and PQ | 25 | 23.8 | 12.4–37.1 | 57.2 | 28.7–67.0 | 3,120 | 940–5,440 | 0 | 0–0 |
| P value for K-S | 0.00001 | 0.00001 | 0.00001 | 0.00001 | |||||
| P value for K-W | 0.2030 | 0.1740 | 0.0600 | 0.3680 | |||||
*
P = percentile; CQ = chloroquine; SP = sulfadoxine-pyrimethamine; AQ = amodiaquine; MQ = mefloquine; AS = artesunate; PQ = primaquine; K-S Kolmogorov-Smirnov test, K-W = Kruskal-Wallis test.