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. 2010 Jul;83(1):90–96. doi: 10.4269/ajtmh.2010.09-0286

Table 5.

Summary of survival analysis and mean time for sexual and asexual parasites to disappear in treated patients, Colombia

Treatment Days with asexual parasites Days with gametocytes
Mean (95% CI)* Mean (95% CI) Mean (95% CI) Mean (95% CI)
CQ and SP 4 (2–6)a 2.4 (1.5–3.3) 19 (18–20)a 18.1 (16.7–19.5)
AQ and SP 2 (1–2)a 1.8 (1.4–2.2) 14 (13–16)a 13.6 (11.8–15.4)
MQ and SP 2 (1–3)a 1.8 (1.2–2.4) 11 (9–14)a 10.4 (8.3–12.5)
AS and SP 1 (1–1)b 0.9 (0.9–1.0) 5 (3–7)b 3.7 (2.2–5.2)
AS and AQ 1 (1–1)c 0.7 (0.6–0.8) 2 (1–4)cd 2.1 (0.5–3.7)
AS and MQ 1 (0–1)cd 0.5 (0.3–0.8) 2 (0–3)d 1.6 (0.0–3.2)
AS, MQ, and PQ 0 (0–1)d 0.4 (0.2–0.6) 1 (0–1)de 0.6 (0.0–1.4)
Breslow statistic = 203.91, P = 0.00001 Breslow statistic 173.64, P = 0.00001
*

CI = confidence interval; CQ = chloroquine; SP = sulfadoxine-pyrimethamine; AQ = amodiaquine; MQ = mefloquine; AS = artesunate; PQ = primaquine. Superscript letters that are not repeated among the treatments show statistically significant differences by the log-rank test or Breslov test.

Parasite mean survival time obtained by using Kaplan-Meier analysis.

Arithmetic mean in days taken for parasites to disappear.