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Surface antigen a determinant amino acid sequence alignment for hepatitis B virus (HBV). The first line sequence is the consensus sequence corresponding to an HBV subgenotype (B1; accession no. D23678) reference strain retrieved from the DNA Data Bank of Japan/GenBank database. Dots in the alignment indicate positions with amino acids identical to the HBV/B1 consensus sequence. The a determinant region in the S gene is indicated with a different color.
