Table 2.
Genomic variability of HBV in HBsAg-negative carriers, East Java, Indonesia*
| ID | Anti-HBs/ Anti-HBc | Amino acid mutation in the Pre-S/S region | Nucleotide mutation in the Pre-C/CP region | ||
|---|---|---|---|---|---|
| Pre-S region | S region | A1762T/ G1764A | G1896T | ||
| L29 | –/+ | K24R,Q56P,I57T,C64S, S113T | T126I, T143S | – | – |
| L33 | –/+ | K24R,Q56P,I57T,C64S | Wild | UD | UD |
| L44 | +/− | K24R,Q56P,I57T,C64S | Wild | + | – |
| L62 | +/+ | S113T | T126I, T143S | – | – |
| L119 | –/+ | K24R,Q56P,I57T,C64S, S113T | T126I, T143S | – | – |
*
HBV = hepatitis B virus; HBsAg = hepatitis B surface antigen; ID = identification; anti-HBs = antibody to HBsAg; anti-HBc = antibody to hepatitis B core antigen; S = surface; C = core; CP = core promoter; UD = undetermined.