Table 2.
Power (casual SNP randomly distributed throughout whole genome)
p value threshold | No adjustment | Known strata | Standard PCA | Shrinkage PCA | Thinning PCA | Regression PCA |
---|---|---|---|---|---|---|
10−5 | 0.827 | 0.844 | 0.839 | 0.842 | 0.842 | 0.841 |
10−6 | 0.738 | 0.763 | 0.754 | 0.759 | 0.759 | 0.757 |
5 × 10−7 | 0.707 | 0.734 | 0.721 | 0.728 | 0.726 | 0.725 |
10−7 | 0.636 | 0.662 | 0.650 | 0.657 | 0.653 | 0.654 |
Columns 2–7: Each table entry represents the proportion of 10,000 simulations in which the causal SNP was rejected at the given p value threshold.