Table 3.
Power (casual SNP randomly distributed in the large LD block)
p value threshold | No adjustment | Known strata | Standard PCA | Shrinkage PCA | Thinning PCA | Regression PCA |
---|---|---|---|---|---|---|
10−5 | 0.973 | 0.970 | 0.296 | 0.967 | 0.969 | 0.967 |
10−6 | 0.923 | 0.917 | 0.155 | 0.909 | 0.914 | 0.909 |
5 × 10−7 | 0.902 | 0.894 | 0.125 | 0.884 | 0.892 | 0.885 |
10−7 | 0.835 | 0.827 | 0.074 | 0.814 | 0.824 | 0.816 |
Columns 2–7: Each table entry represents the proportion of 10,000 simulations in which the causal SNP was rejected at the given p value threshold.