Table 1.
Autoshaping, pretraining, and discrimination performance in 5-HTT null mutant mice
| WT | HET | KO | |
| Autoshaping sessions | 1.9 ± 0.6 | 2.3 ± 0.9 | 2.0 ± 0.6 |
| Pretraining | |||
| Respond phase sessions | 4.4 ± 1.6 | 3.4 ± 0.4 | 3.6 ± 1.1 |
| Punish phase sessions | 6.8 ± 1.8 | 6.1 ± 1.9 | 7.3 ± 1.9 |
| Discrimination | |||
| Total trials | 613.0 ± 104.2 | 389.1 ± 73.0 | 456.6 ± 157 |
| Total errors | 184.3 ± 36.3 | 111.3 ± 25.1 | 133.9 ± 47.2 |
| Total correction errors | 412.1 ± 88.2 | 225.9 ± 37.6 | 261.1 ± 81.8 |
| Total trials omitted | 22.4 ± 7.7 | 4.6 ± 3.6 | 17.9 ± 10.2 |
| Average stimulus reaction time (s) | 8.0 ± 1.0 | 6.0 ± 1.0 | 8.2 ± 0.4 |
| Average reward retrieval latency (s) | 2.7 ± 0.5 | 2.8 ± 0.8 | 2.5 ± 0.4 |
Genotypes did not significantly differ in autoshaping, pretraining, or discrimination performance, although there was a nonsignificant trend for HET and KO mice to require fewer trials make fewer errors to reach criterion than WT controls. n = 8–10 per genotype. Data are means ± standard errors of the mean.