Table 5.
Correlation between Ch4 volume and gray matter volume in MCI
| Brain region | Side | CS | Coordinates |
P | T31 | ||
| x | y | z | |||||
| Putamen | R | 1810 | 20 | 11 | −8 | 0.001 | 4.82 |
| Orbital gyrus (BA 11) | R | 9 | 44 | −13 | 0.001 | 3.3 | |
| Caudate head | R | 11 | 15 | 3 | 0.005 | 3.14 | |
| Putamen | L | 1614 | −25 | 10 | −8 | 0.001 | 5.11 |
| Ventral striatum | L | −15 | 13 | −7 | 0.001 | 4.69 | |
| Caudate head | L | −14 | 12 | 3 | 0.001 | 3.66 | |
| Superior frontal gyrus (BA 9) | R | 395 | 11 | 57 | 30 | 0.001 | 4.33 |
| Middle frontal gyrus (BA 10) | L | 352 | −43 | 41 | 0 | 0.001 | 4.38 |
| Middle frontal gyrus (BA 10) | L | −31 | 41 | 6 | 0.005 | 3.17 | |
| Precuneus (BA 7) | L | 267 | −2 | −65 | 31 | 0.001 | 4.17 |
| Thalamus (anterior nucleus) | R | 59 | 5 | −5 | 7 | 0.001 | 3.40 |
Note: L/R (left and right cerebral hemispheres, respectively). CS (cluster size) was set at 50 contiguous voxels. Coordinates in bold delineate a cluster and the peak-effect coordinate (in the Talairach reference space) within the cluster. Subsequent nonbold coordinates identify further peaks within the same cluster. Statistical values are uncorrected voxel-level P values and their corresponding T-values (31 degrees of freedom). BA (Brodmann area).