Table 6.

Correlation between Ch4p volume and gray matter volume in MCI

Brain region	Side	CS	Coordinates			P	T31
			x	y	z
Medial frontal gyrus (BA 9)	R	689	8	46	28	0.001	4.58
Posterior hippocampus	L	355	−33	−30	−5	0.001	4.46
Middle frontal gyrus (BA 10)	L	285	−31	41	6	0.001	4.39
Uncus (BA 20)	L	755	−36	−14	−27	0.001	4.11
Temporal pole (BA 38)	L		−33	7	−28	0.001	3.62
Ch4p/extended amygdala	L	1096	−19	−10	−10	0.001	4.08
Parahippocampal gyrus (BA 35)	L		−23	−22	−19	0.001	3.76
Parahippocampal gyrus (BA 35)	L		−17	−16	−27	0.001	3.41
Subcallosal gyrus (BA 25)	R	267	11	21	−4	0.001	4.01
Subcallosal gyrus (BA 25)	R		10	32	−9	0.001	3.58
Posterior cingulate/precuneus (BA 31)	L	365	−13	−55	26	0.001	4.01
Superior temporal gyrus (BA 22)	L	295	−50	−36	3	0.001	3.71
Anterior cingulate (BA 32)	R	197	11	42	7	0.001	3.60
Posterior hippocampus	R	124	32	−30	−1	0.001	3.54
Middle temporal gyrus (BA 21)	R	299	42	−3	−21	0.001	3.50
Temporal pole (BA 38)	R		36	8	−24	0.001	3.30
Subcallosal gyrus (BA 25)	L	109	−12	19	−5	0.001	3.34
Middle temporal gyrus (BA 21)	L	194	−47	−14	−19	0.001	3.31
Middle temporal gyrus (BA 21)	L		−48	−3	−23	0.005	3.20
Fusiform gyrus (BA 37)	R	186	38	−55	−10	0.001	3.25
Middle temporal gyrus (BA 37)	R		41	−52	−3	0.005	3.08
Angular gyrus (BA 39)	L	81	−43	−63	17	0.005	3.22
Parahippocampal gyrus (BA 28)	R	59	22	−20	−19	0.005	3.19
Parahippocampal gyrus (BA 28)	R		18	−17	−27	0.005	2.97
Superior temporal gyrus (BA 41)	R	96	40	−38	12	0.005	3.14
Middle temporal gyrus (BA 21)	L	74	−50	−26	−12	0.005	2.97
Superior temporal gyrus (BA 21)	L		−51	−22	−4	0.005	2.89

Note: L/R (left and right cerebral hemispheres, respectively). CS (cluster size) was set at 50 contiguous voxels. Coordinates in bold delineate a cluster and the peak-effect coordinate (in the Talairach reference space) within the cluster. Subsequent nonbold coordinates identify further peaks within the same cluster. Statistical values are uncorrected voxel-level P values and their corresponding T-values (31 degrees of freedom). BA (Brodmann area).