FIG 5 .

Stable SeqA binding targets. The figure shows ChIP-chip data for SeqA binding close to the pyrD (A) and mukF (B) genes in vivo. Data presented were generated from unsynchronized cultures of E. coli (time point A), cultures where chromosome replication had been blocked for 1 h (time point B), and cultures where chromosome replication had been reinitiated in synchronicity for a period of 6 min (time point C). The ChIP-chip data sets have been aligned with a graph showing the locations of and frequencies at which GATC sites occur in the underlying DNA sequence.