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SeqA binding is reduced in rRNA operons. The figure shows ChIP-chip data for SeqA and RNA polymerase binding close to the replication origin and the rrnC rRNA operon. The data were generated from synchronized cultures of E. coli where chromosome replication had been reinitiated in synchronicity for a period of 6 min. The ChIP-chip data sets have been aligned with a graph showing the locations of and frequencies at which GATC sites occur in the underlying DNA sequence.
