TABLE 1 .

Stable SeqA targets outside the replication origin

Gene	Function(s)	SeqA binding signala	Length (bp)	No. of GATC motifs	No. of GATC motifs/1,000 bpb
pyrD	Pyrimidine biosynthesis	12.6	1,011	13	12.9
dmsA	Dimethyl sulfoxide reductase, anaerobic respiration	7.2	2,445	20	8.2
rlmL	rRNA methylation, methyltransferase	7.9	2,109	21	10.0
uup	Possible role in replication fork progression	6.0	1,908	14	7.3
mukF	Chromosome segregation	5.6	1,323	12	9.1
smtA	S-Adenosylmethionine-dependent methyltransferase	3.9	786	7	8.9
ybiW	Predicted pyruvate formate lyase	4.2	2,433	18	7.4
etk	Protein-tyrosine kinase	3.6	2,181	15	6.9
potI	Putrescine transporter subunit	3.2	846	10	11.8
potH	Putrescine transporter subunit	2.7	954	12	12.6
ygiQ	Unknown, located in operon with ftsP	2.7	2,220	21	9.5
nfrA	Bacteriophage N4 receptor	2.6	2,973	14	4.7

^aTaken from time point B.

^bEscherichia coli K-12 has an average of 4.1 GATC motifs per 1,000 bp.