Table 4.
Current microbicide clinical trials
| Phase | Drug (s) | Route | Study Title | N | Countries |
|---|---|---|---|---|---|
| 2B | Tenofovir gel Oral tenofovir Truvada | V/O | MTN-003 (VOICE) | 5,000 | Malawi , South Africa, Zimbabwe, Zambia, Uganda, |
| 2B | Tenofovir gel | V | CAPRISA-004 | 980 | South Africa |
| 2 | Tenofovir gel Oral tenofovir | V/0 | MTN-001 | 144 | South Africa, USA, Uganda |
| 1 | TMC-120 gel (4759 & 4789) | V | IPM020 | 180 | USA |
| 1 | TMC-120 gel (4759) | V | IPM014A | 320 | Kenya, Malawi, Rwanda, South Africa, Tanzania |
| 1 | TMC-120 gel (4789) | V | IPM014B | 320 | Kenya, Malawi, Rwanda, South Africa, Tanzania |
| 1 | TMC-120 ring | V | IPM024 | 16 | Belgium |
| 1 | VivaGel | V | MTN-004 | 61 | USA |
| 1 | Tenofovir gel | V | MTN-002 | 16 | USA |
| 1 | Tenofovir gel | V | NIAID/DAIDS/AECOM | 24 | USA |
| 1 | Tenofovir gel Oral tenofovir | R/O | RMP-02/MTN-006 | 18 | USA |
| 1 | Tenofovir gel | R | MTN-007 | 60 | USA |
| 1 | Acidform gel | V | AF 020 AECOM | 36 | USA |
Vaginal (V), Oral (O), Rectal (R), International Partnership for Microbicides (IPM), Microbicide Trials Network (MTN), Albert Einstein College of Medicine (AECOM)