Table 2.
Safety measures at visit 1 and visit 2 in patients receiving chicory
| Variable Measured | Cohort 1 | Cohort 2 | Cohort 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| (N = 4)* | (N = 4) | (N = 13) | |||||||
| Visit 1 | Visit 2 | P** | Visit 1 | Visit 2 | P | Visit 1 | Visit 2 | P | |
| BP Syst (mm Hg) | 136 ± 9.3 | 128 ± 9.9 | 0.40 | 144 ± 7.8 | 141 ± 3.5 | 0.80 | 138 ± 5.7 | 142 ± 5.4 | 0.39 |
| BP Diast (mm Hg) | 83 ± 6.6 | 82 ± 5.5 | 0.86 | 78 ± 10.1 | 88 ± 3.7 | 0.46 | 96 ± 2.3 | 88 ± 3.4 | 0.04 |
| HR (BPM) | 69 ± 4.2 | 77 ± 4.6 | 0.01 | 74 ± 9.2 | 76 ± 9.4 | 0.74 | 72 ± 3.7 | 71 ± 4.3 | 0.65 |
| WBC† (cell/mm3) | 6.1 ± 0.6 | 6.1 ± 0.3 | 0.48 | 6.6 ± 1.2 | 5.9 ± 0.9 | 0.20 | 6.9 ± 0.5 | 6.6 ± 0.2 | 0.34 |
| Hgb (g/dL) | 12.8 ± 0.8 | 12.6 ± 0.7 | 0.23 | 14.4 ± 0.9 | 14.5 ± 0.8 | 0.25 | 14.6 ± 0.2 | 14.1 ± 0.3 | 0.02 |
| Creatinine (mg/dL) | 0.78 ± 0.08 | 0.78 ± 0.07 | 1 | 0.68 ± 0.11 | 0.70 ± 0.11 | 0.39 | 0.83 ± 0.04 | 0.84 ± 0.04 | 0.67 |
| AST (U/L) | 17.3 ± 1.8 | 17.8 ± 0.5 | 0.81 | 24.0 ± 3.5 | 25.0 ± 5.0 | 0.57 | 21.9 ± 2.4 | 22.3 ± 2.4 | 0.86 |
* Patients included in this analysis were those receiving chicory who had lab values available at both baseline and final visits. Values represent mean and S.E.M.
** P values calculated using paired t-test, V1 vs V2.
†Normal range: WBC 4.1-11.1 × 10/μL.