Figure 1.
Whole cell currents recorded from relay neurons in thalamic slice preparations show characteristics indicative for K2P9.1 channels. (A) Mean ramp currents under control recording conditions (ctrl) and after removal of extracellular divalent cations (div. cation free). Inset: Currents were evoked by ramping the membrane potential from -35 mV to -125 mV over 800 ms. (B) I-V relationship of the divalent cation-sensitive current component shows characteristics indicative of TASK channels. I = current; ISO = standing outward current; VM = membrane potential.