Table 1.
Anthropometry and exercise capacity in 23 COPD patients and 12 age-matched healthy subjects.
|
Healthy Subjects (n = 12) |
Mild COPD (n = 8) |
Moderate COPD (n = 9) |
Severe COPD (n = 6) |
P-value | |
|---|---|---|---|---|---|
| Age (years) | 61.9 ± 7.9 | 60.8 ± 7.5 | 61.1 ± 3.8 | 64.0 ± 8.7 | ns |
| Height (cm) | 170.2 ± 10.4 | 169.5 ± 10.4 | 170.5 ± 8.2 | 167.7 ± 6.3 | ns |
| Weight (kg) | 77.1 ± 12.4 | 78.4 ± 21.0 | 82.4 ± 22.0 | 66.4 ± 11.3 | ns |
| BMI (kg/m2) | 26.6 ± 3.6 | 27.0 ± 5.4 | 28.0 ± 5.5 | 23.6 ± 3.9 | ns |
| FEV1.0 (% of expected) | 115 ± 12 | 86 ± 6 | 48 ± 8* | 26 ± 3* | < 0.001 |
| PaO2 (kPa) | 11.1 ± 1.3 | 10.5 ± 1.5 | 9.5 ± 1.1 | 9.2 ± 1.1* | 0,01 |
| PaCO2 (kPa) | 5.2 ± 0.3 | 4.8 ± 0.3 | 5.0 ± 0.6 | 5.6 ± 0.7* | 0.02 |
| Distance walked in 6 min (m) | 502 ± 52 | 422 ± 43 | 336 ± 46* | 248 ± 91* | < 0.001 |
Data are presented as mean ± SD.
* Significant difference compared to healthy subjects.
n = number of test subjects; BMI = body mass index; FEV1.0 = forced expiratory volume in one second; PaO2 = partial arterial pressure for oxygen; PaCO2 = partial arterial pressure for carbon dioxide; ns = not significant.