Figure 3.

The T_C1, T_H1 and T_H17 subsets in AML patients and healthy controls. The levels of circulating T_C1, T_H1 and T_H17 cells were investigated for patients with untreated AML (AML, n = 16), patients with chemotherapy-induced cytopenia (Cytopenia, n = 16; the first cohort of patients) and during hematopoietic reconstitution after chemotherapy (Reconstitution, n = 6); these results were compared with healthy controls (n = 30). The levels for each of the subsets are presented as the percentage of each cell type among the parent population; i.e. T_C1 cells among CD8⁺ cells, T_H1 and T_H17 cells among CD8^- T cells and T_REG cells among CD4⁺ T cells. All results are presented as median (horizontal line), 25^th to 75^th percentiles (boxes) and variation range (whiskers). The percentages of total T cells or T cell subsets did not show any age-dependent variation among the healthy controls. Statistically significant differences are presented at the top of the figure (Mann-Whitney test).