Table 4.
Comparative summary and main findings of prostate viral infection reports
| Country/Study Description |
Pathogen | Samples (+) | Total | Findings | Reference |
|---|---|---|---|---|---|
| Sweden/201 prostate tissue samples from patients with BPH that later progressed to PC and 201 matched controls that did not. |
Epstein-Barr Virus. JCV. BKV, HPVs, CMV. Adenovirus, HSV1 and 2 C.albicans. |
31 10 0 0 2 |
43 (352) |
There were no differences in the prevalence of adenovirus, herpesvirus, papillomavirus, polyoma virus and C. albicans DNA. |
Bergh J. British Journal of Cancer 2007. |
| Baltimore, USA/30 PC subjects for bacterial DNA and 200 PC cases for viral-parasite DNA detection. |
BKV. Chlamydia T. CMV. Epstein-Barr Virus. HPVs, XMRV. |
1 1 1 16 0 |
18 (200) |
Most prostatectomies (87%) contain bacterial DNA from one or more species. The majority of individual tissue core samples were negative, suggesting regional heterogeneity in the presence of bacteria and a lack of a generalized or ubiquitous prostatic flora. |
Sfanos KS. The Prostate 2008. |
| Greece/42 samples of prostatic malignancies. |
BKV. JCV. HPVs.. |
8 0 2 |
10 (42) |
BKV was frequently detected and could play a relevant role in the development and progression of human PC, whereas HPV does not seem to be implicated in this type of human neoplasia. |
Balis V. Int J Biol Markers. 2007. |
| LongBeach, USA/ 12 PC Fresh frozen tissues and 20 paraffin-embedded archival samples. |
HPVs. JCV. BKV. |
0 (20), 6 (12) 10 (20),6 (12) 0 (20), 3 (12) |
10 (20) And 7(12) |
The prostate is a complex habitat where mixed infections with oncogenic DNA viruses frequently occur and opens the discussion to the potential role of these viruses in the PC. |
Zambrano A, Prostate 2002. |
| Monterrey, Mexico/55 Cases of PC and 75 Controls. |
JCV, BKV, SV40. HPVs. HCMV. XMRV. |
0 15 6 1 |
22 (130) |
HPV frequency was significantly higher in PC cases than in controls; this finding suggests their participation in PC develpment or tumor progression. |
This work. |