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Sensitivity and specificity of the sCD26 at different cut-off values for separating individuals with no colorectal pathology from those with CRC.
| Cut-off (ng/mL) | Sensitivity (95% CI) | Specificity (95% CI) | +LR | -LR |
|---|---|---|---|---|
| 390 | 57.6% (38.2-74.5) | 83.8% (72.9-91.6) | 3.6 | 0.5 |
| 410 | 72.7% (54.5-86.7) | 80.9% (69.5-89.4) | 3.8 | 0.3 |
| 460 | 81.8% (64.5-93.0) | 79.4% (67.9-88.3) | 4.0 | 0.2 |
| 500 | 84.9% (68.1-94.8) | 72.1% (59.9-82.3) | 3.0 | 0.2 |
+LR: Positive likelihood ratio; -LR: Negative likelihood ratio.
