Table 1.
Marginal likelihood of different models
| Protein | PDB IDs | Student t | K | Laplace | Gauss |
|---|---|---|---|---|---|
| GroEL | 1AON-1OEL | -4328.57 | -4307.22 | -5132.84 | -5722.35 |
| DNA Pol | 1IH7-1IG9 | -5574.80 | -5750.12 | -6340.01 | -8011.05 |
| RAN | 1RRP-1BYU | -1124.86 | -1176.53 | -1795.92 | -2286.10 |
| Topo II | 1BGW-1BJT | -4496.17 | -4553.50 | -7210.74 | -8042.00 |
| Pneumolysin | 2BK2-2BK1 | -2692.73 | -2465.09 | -5195.85 | -5491.90 |
| ER | 3ERD-3ERT | -538.11 | -622.69 | -1290.81 | -1980.96 |
| RNA Pol | 1QLN-1MSW | -5296.61 | -5455.79 | -8471.69 | -10168.07 |
| Adenylate Kinase | 1AKE-4AKE | -1499.73 | -1502.75 | -1685.11 | -2000.35 |
| Myosin | 1B7T-1DFK | -4819.91 | -5046.02 | -6380.11 | -7701.83 |
| Synthetic data | Student t | -9179.46 | -9253.48 | -12465.97 | -13951.94 |
| Synthetic data | Gauss | -5108.73 | -5112.43 | -5077.97 | -5115.98 |
Logarithm of the marginal likelihood P(M|D) of the different displacement models obtained for nine structure pairs undergoing domain movements. Highlighted in boldface are the maximum log-marginal likelihood values. The last two rows at the bottom report the log-marginal likelihoods for synthetic data generated according to a Student t and a Gauss distribution.