Skip to main content
. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Cancer Res. 2010 Jul 7;70(15):6377–6383. doi: 10.1158/0008-5472.CAN-10-1180

Figure 4. Inhibition of TMEPAI expression decreases human breast tumor growth in nude mice.

Figure 4

A. Reduced breast tumorigenic potential in vivo of TMEPAI knockdown cells as measured by tumor volume (*P< 0.05). Inset shows representative tumors. B. Reduced expression of VEGF and Ki67 in tumors formed by TMEPAI knockdown cells compared to cells expressing control shRNA. C. Relative expression of HIF-1α in control and TMEPAI knockdown cells and xenograft breast tumors. HeLa cells treated with cobalt chloride were used as positive control for HIF-1α expression. D. Expression of pAkt, PTEN, p27kip1 and HIF-1α and TMEPAI in cells expressing control shRNA and TMEPAI shRNA.