Table 1.
Pre-infusion of scala media with the P2X antagonist PPADS (1,000 μM, 50 nL) prior to ATP (100 μM, 10 nL) caused a significant reduction in the magnitude of change in EP and CoPR
| No PPADS | PPADS | |||
|---|---|---|---|---|
| Before ATP | During ATP | Before ATP | During ATP | |
| EP | 118.8 ± 4.2 | 99.1 ± 4.2* | 110.7 ± 3.9 | 106.5 ± 4.5 |
| CoPR | 6.8 ± 0.2 | 6.1 ± 0.1* | 7.2 ± 0.3 | 6.8 ± 0.3 |
Data presented as mean ± SEM
*p < 0.01 (when compared between before and during ATP)