Table 1.
Mean values of histomorphometric parameters, expressed as BV/TV (%) and Ct-B-Ar (mm2), in both trabecular and cortical bone of the four animal groups, 2 months after OVX and at the end of 30 days of treatment.
| 4th lumbar vertebra sagittal sections BV/TV (%) | 5th lumbar vertebra transversal sections BV/TV (%) | Femur sagittal sections of distal epiphysis BV/TV (%) | Femur transversal sections of mid-diaphysis Ct-B-Ar (mm2) | |
|---|---|---|---|---|
| SHAM | 29.2 ± 2.6 | 28.4 ± 1.6 | 32.1 ± 3.1 | 5.740 ± 0.066 |
| C-OVX | 16.8 ± 2.0# | 14.7 ± 2.0### | 6.4 ± 1.3### | 5.888 ± 0.114 |
| F-OVX | 20.5 ± 2.2 | 22.5 ± 2.0#,* | 10.6 ± 1.7### | 5.718 ± 0.105 |
| EB-OVX | 23.3 ± 2.2 | 20.5 ± 0.9#,* | 11.6 ± 1.6### | 5.965 ± 0.050 |
Values are expressed as mean ± SEM.
*
P< 0.05 vs. C-OVX;
#
P< 0.05,
###
P< 0.001 vs. SHAM (anova followed by Newman–Keuls test).
SHAM, sham-operated controls receiving vehicle; C-OVX, ovariectomized controls receiving vehicle; F-OVX, ovariectomized treated with ferutinin; EB-OVX, ovariectomized treated with estradiol benzoate.