Table 2.
Characteristics of patients with iatrogenic hypothyroidism (number of patients = 112)
| Characteristic | Mean (sd) | Percentage |
|---|---|---|
| Age (yr) | 47 (15) | |
| Gender | ||
| Female | 77 | |
| Male | 23 | |
| Height (m) | 1.72 (0.09) | |
| Weight (kg) | 79 (19) | |
| BMI | 28 (7) | |
| Menopausal status | ||
| Premenopausal | 46 | |
| Postmenopausal | 31 | |
| Not applicable | 23 | |
| TSH (mIU/liter) | 105 (75) | |
| FT4 (ng/dl) | 0.23 (0.09) | |
| Serum creatinine (mg/dl) | ||
| All ages | 1.22 (0.30) | |
| <35 yr | 1.09 (0.17) | |
| 35–49 yr | 1.13 (0.23) | |
| 50–64 yr | 1.24 (0.29) | |
| >64 yr | 1.67 (0.27) | |
| GFR (ml/min · 1.73 m2) | ||
| All ages | 64 (21) | |
| <35 yr | 75 (19) | |
| 35–49 yr | 68 (19) | |
| 50–64 yr | 59 (19) | |
| >64 yr | 39 (10) | |
| Baseline serum TSH (mIU/liter) | ||
| All ages | 2.0 (1.5) | |
| <35 yr | 1.7 (1.3) | |
| 35–49 yr | 1.7 (1.1) | |
| 50–64 yr | 2.1 (1.2) | |
| >64 yr | 3.1 (2.5) | |
| Days off l-T4 | 39 (5) | |
| Days off T3 | 13 (1) | |
| Thyroglobulin (ng/ml) | 85 (444), median 0 | |
| Presence of thyroglobulin antibodies | ||
| No | 83 | |
| Yes | 17 | |
| Distant metastases | ||
| No | 87 | |
| Yes | 13 | |
| Presence of thyroid remnant | ||
| Yes | 86 | |
| No | 14 | |
| Type of differentiated thyroid cancer | ||
| Papillary | 74 | |
| Follicular | 16 | |
| Other variant | 10 | |
| Years elapsed since thyroidectomy | 0.5 (1.2) | |
| Years elapsed since last radioiodine therapy | 0.3 (0.7) | |
| Initial radioiodine therapy | 79 | |
| Subsequent radioiodine therapy or diagnostic scanning | 21 |