(A) Overall survival according to the GOELAMS index related to the number of criteria observed at diagnosis among 4 pejorative prognostic factors (PF): Ki67>26%, ECOG>1, B symptoms and LDH>N. g1 = group with 3 or 4 PF, g2 = group with 1 or 2 PF and g3 = group without PF. (B) Overall survival according to the MIPI, Low=low-risk, Int = intermediate-risk and High = high-risk.