Table 1.
SNP locations, genotype frequencies, amino acid changes, and ID numbers for mutations in MYH 2, 3, and 8.
| Gene | Exon/Intron | Patient Genotype Frequencies (% homozygous wild type, heterozygote, homozygous variant) | Control Genotype Frequencies (% homozygous wild type, heterozygote, homozygous variant) | Amino Acid Change | ID # | ||||
|---|---|---|---|---|---|---|---|---|---|
| MYH2 | Intron | 28 | 54 | 18 | 33 | 42 | 24 | rs719277 | |
| MYH2 | Intron | 24 | 48 | 28 | 33 | 46 | 21 | rs3744565 | |
| MYH2 | Intron | 42 | 40 | 19 | 32 | 38 | 30 | rs2277651 | |
| MYH3 | Intron | 27 | 57 | 16 | 31 | 60 | 9 | rs2239934 | |
| MYH3 | Intron | 50 | 39 | 10 | 45 | 41 | 14 | rs2285468 | |
| MYH3 | Intron | 31 | 59 | 9 | 32 | 53 | 14 | rs876660 | |
| MYH3 | Exon | 40 | 53 | 7 | 37 | 47 | 17 | A-to-T | rs2285477 |
| MYH3 | Intron | 0 | 100 | 0 | 0 | 100 | 0 | rs2239936 | |
| MYH8 | Intron | 52 | 20 | 28 | 44 | 23 | 32 | rs4791407 | |
| MYH8 | Exon | 25 | 75 | 0 | 28 | 72 | 1 | R-to-W | rs8069834 |
| MYH8 | Intron | 16 | 75 | 9 | 17 | 81 | 2 | rs2277648 | |