Skip to main content
. Author manuscript; available in PMC: 2011 Jul 29.
Published in final edited form as: Neuron. 2010 Jul 29;67(2):280–293. doi: 10.1016/j.neuron.2010.06.020

Figure 5. The NMDA component of the fitted response is blocked by D-AP-5.

Figure 5

A. Response traces and I-V plots for an OFF α cell under control conditions and in the presence of D-AP-5 (100 μM). The I-V plot becomes more linear in the presence of D-AP-5.

B. Contrast response functions for the three fitted conductances. The NMDA component of the fit was suppressed to near zero values in the presence of D-AP- 5. The number of cells at each contrast is indicated below the points in the D-AP-5 condition.

C. Same format as A. for an OFF δ cell. In the presence of D-AP-5, the U-shaped I-V relationship changed to a negative linear slope, indicating the suppression of a baseline inhibitory conductance (disinhibition).

D. Same format as B. for OFF δ cells.