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. 2010 Apr 15;182(2):220–229. doi: 10.1164/rccm.200911-1698OC

Figure 1.

Figure 1.

MicroRNAs are differentially expressed in idiopathic pulmonary fibrosis (IPF). (A) The heat map on the left represents global microRNA expression. The heat map on the right represents statistically significant (P < 0.05), differentially expressed microRNAs. Up-regulated microRNAs are shown in progressively brighter shades of yellow, depending on the fold difference, and down-regulated microRNAs are shown in progressively brighter shades of purple. Gray, expression of microRNAs that show no difference between the two groups being compared. The names of the down-regulated microRNAs are provided to the right of the heat map. (B) Quantitative real-time polymerase chain reaction (qRT-PCR) confirmation of the microarray results demonstrates significant changes in all qRT-PCR–measured microRNAs (P < 0.05).