Table 5.
Predictors of SVR by multiple logistic regression analysis. Input variables were age, gender, fibrosis group (mild (Ishak 0–3), severe (4–6)), viral genotype (2 and 3 versus 1 and 4), viral load, BMI, CD8+CD45RO+ and CD4+CD45RO+ lymphocyte telomere length. Non-significant variables were removed by backward stepwise regression.
| Logistic regression |
Backward LR stepwise regression |
|||||||
|---|---|---|---|---|---|---|---|---|
| Variable | Comparison | Wald | OR (95% CI) | p | Comparison | Wald | OR (95% CI) | p |
| Age | - | 0.72 | 0.97 (0.89, 1.05) | 0.40 | ||||
| Sex | Male vs. female | 0.53 | 1.74 (0.39, 7.66) | 0.47 | ||||
| Fibrosis | Severe vs. Mild | 3.03 | 0.18 (0.03, 1.24) | 0.08 | ||||
| Genotype | 2/3 vs. 1/4 | 1.90 | 2.17 (0.71, 6.89) | 0.17 | ||||
| Viral load | - | 5.74 | 1.00 (1.00, 1.00) | 0.02 | - | 5.58 | 1.00 (1.00, 1.00) | 0.02 |
| BMI | - | 0.007 | 1.00 (0.88, 1.12) | 0.93 | ||||
| CD8+45RO+ telomere length | - | 0.09 | 1.01 (0.96, 1.06) | 0.76 | ||||
| CD4+45RO+ telomere length | - | 2.59 | 1.06 (0.99, 1.14) | 0.11 | - | 11.28 | 1.08 (1.03, 1.13) | 0.001 |
Bold indicates significant results.