Table 1.
Subject characteristics
| Variable | Weight Loss (n=26) | Control (n=14) | ||
|---|---|---|---|---|
| Baseline | 16 Weeks | Baseline | 16 Weeks | |
| Age (years) | 49.5 ± 2.5 | ------ | 40.8 ± 3.3‡ | ------ |
| Male/Female (no.) | 15/11 | ------ | 9/5 | ------ |
| Systolic BP (mmHg) | 122 ± 2 | 116 ± 3 | 119 ± 4 | 121 ± 3 |
| Diastolic BP (mmHg) | 72 ± 2 | 69 ± 2 | 70 ± 2 | 67 ± 2 |
| Rest HR (beats/min) | 67 ± 2 | 62 ± 2*† | 64 ± 2 | 68 ± 3 |
| Total cholesterol (mg/dl) | 207 ± 8 | 184 ± 6*† | 197 ± 6 | 189 ± 6 |
| LDL-cholesterol (mg/dl) | 128 ± 8 | 113 ± 6 | 119 ± 6 | 116 ± 6 |
| HDL-cholesterol (mg/dl) | 48 ± 3 | 47 ± 2 | 42 ± 3 | 41 ± 3 |
| Triglycerides (mg/dl) | 157 ± 21 | 113 ± 10 | 181 ± 30 | 155 ± 23 |
| VLDL-cholesterol (mg/dl) | 31 ± 4 | 23 ± 2 | 36 ± 6 | 31 ± 5 |
| Total/HDL-cholesterol ratio | 4.6 ± 0.3 | 4.1 ± 0.2 | 5.1 ± 0.5 | 4.7 ± 0.4 |
| Glucose (mg/dl) | 93 ± 2 | 91 ± 1 | 92 ± 1 | 90 ± 1 |
| Insulin (μU/L) | 9.0 ± 1.1 | 6.7 ± 0.9*† | 9.8 ± 1.2 | 10.4 ± 1.2 |
| HOMA-IR | 2.1 ± 0.3 | 1.5 ± 0.2*† | 2.2 ± 0.3 | 2.4 ± 0.3 |
| Si ([mU/L]−1/min) | 3.7 ± 0.5 | 5.6 ± 0.6 | 3.0 ± 0.6 | 4.3 ± 1.2 |
| Sg ([mU/L−1/min) | 0.023 ± 0.004 | 0.020 ± 0.004 | 0.036 ± 0.012 | 0.019 ± 0.002 |
Values are mean ± standard error;
*
P<0.05 vs. Pre;
†
P<0.05 group (Weight loss, Control) × time (Pre, Post) interaction;
‡
P<0.05 vs. Weight Loss; BP, blood pressure;
LDL, low-density lipoprotein; HDL, high density lipoprotein; VLDL, very-low density lipoprotein; HOMA-IR, homeostasis model assessment of insulin resistance; Si, insulin sensitivity; Sg, glucose sensitivity.