. Author manuscript; available in PMC: 2011 Jun 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2010 Jan 29;16(6):751–771. doi: 10.1016/j.bbmt.2010.01.012

Table 3.

ESC-related genes that are activated in CD8⁺ T_E

Gene symbol	Gene ID#	Fold Change		Gene symbol	Gene ID#	Fold Change		Gene symbol	Gene ID#	Fold Change		Gene symbol	Gene ID#	Fold Change		Gene symbol	Gene ID#	Fold Change
Gene symbol	Gene ID#	T_MSC/T_N	T_E/T_N	Gene symbol	Gene ID#	T_MSC/T_N	T_E/T_N	Gene symbol	Gene ID#	T_MSC/T_N	T_E/T_N	Gene symbol	Gene ID#	T_MSC/T_N	T_E/T_N	Gene symbol	Gene ID#	T_MSC/T_N	T_E/T_N
Cell cycle				Ubiquitin/Proteolysis/Proteasome				Transcription/Transcription regulation				Receptor/Signal transduction				Microtubule-based process
Ccnb1	268697	2.28	16.85	Cdc20	107995		5.27	Mdfic	16543	2.77	18.58	Spp1	20750		4.52	Prc1	233406	1.86	12.05
Sgol1	72415		11.04	Capn2	12334		2.34	Prdm1	12142		10.62	Aurka	20878		4.47	Cks2	66197	4.85	11.65
Chek1	12649	2.6	10.34	Xpnpep1	170750		2.32	Tacc3	21335		6.06	Exo1	26909		4.02	Anln	68743		4.82
Cks1b	54124	2.58	9.51	Ide	15925		2.28	Csda	56449		5.52	Hif1a	15251		3.71	Dstn	56431		1.74
Cdkn1a	12575		9.17	Coq3	230027	1.67	2.12	Cdkn2b	12579		4.89	Csrp2	13008		3.01	Cytokinesis
Plk1	18817		7.54	Psma1	26440		1.99	Plagl1	22634		3.25	Sap30	60406		2.5	Igfbp7	29817		2.68
Aspm	12316		7.53	Psmb2	26445	1.55	1.78	Sub1	20024		2.62	Dusp16	70686		2.3	Wisp1	22402		2.26
Ect2	13605		6.86	Psmc2	19181		1.63	Myef2	17876		2.09	Rap2a	76108		2.27	Miscellaneous
Itgb1	16412		5.58	Psmb5	19173		1.62	Gtf2e2	68153		1.99	Bax	12028		1.84	Fignl1	60530	3.2	15.73
Ccne1	12447		5.31	Psmd6	66413		1.57	Tceb1	67923		1.95	Pex7	18634	1.6	1.74	Trip13	69716	1.88	8.69
Syce2	71846		5.16	Psma3	19167		1.55	Polr3k	67005		1.77	Bdnf	12064		1.72	Pcbp4	59092		6.39
Cdc25c	12532		4.72	Psma5	26442		1.55	Bzw1	66882		1.68	Gnb1	14688		1.69	Tmem49	75909	2.26	6.27
Ccnf	12449		3.96	Metabolism				Cnot7	18983		1.63	Hnrpab	15384		1.65	Tacstd1	17075		5.17
Dlg7	218977		2.72	Gldc	104174		23.94	Klf9	16601		1.6	Ddx1	104721		1.65	Smoc2	64074		4.05
Cdkn2a	12578		2.55	Gsto1	14873	2.29	7.34	Mtdh	67154		1.57	Inhbb	16324		1.64	Synpo	104027	1.75	3.68
Mybl2	17865		2.43	Bcat1	12035		5.54	Nfyb	18045		1.52	Nasp	50927		1.61	Tipin	66131		3.5
Ran	19384		1.89	Myo5a	17918	1.55	4.68	RNA processing				Sfrs1	110809		1.61	Ccdc99	70385		2.81
Ccng1	12450		1.84	Asns	27053	2.95	3.87	Syncrip	56403	1.79	2.88	Snrpd1	20641		1.55	Lactb2	212442	1.64	2.68
Erh	13877	1.67	1.74	Gcat	26912		2.71	Hnrpll	72692		2.73	Hrb	15463		1.55	Gmfb	63985	1.67	2.64
Psmd1	70247		1.69	Shmt1	20425	1.53	2.55	Ell2	192657		2.42	Rab1	19324		1.53	Wbp5	22381		2.42
Cops5	26754		1.64	Uxs1	67883		2.48	Ncbp2	68092	1.9	2.01	Vdac3	22335		1.52	Errfi1	74155	1.54	2.4
DNA replication/Repair				Hmgcr	15357		1.96	Snrpa1	68981		1.91	Transport (Protein/Ion)				Ccdc80	67896		2.34
Rrm2	20135	9.19	60.07	Pfkfb1	18639		1.8	Cstf3	228410		1.84	Kif20a	19348		4.26	Nucks1	98415		2.3
Cdc6	23834	5.09	21.54	Lypla1	18777		1.79	Sfrs3	20383		1.71	Arl5a	75423		3.8	Mpdu1	24070	1.85	2.29
Il1rl1	17082		19.15	Ywhah	22629		1.74	Cops2	12848		1.7	Snx10	71982	1.97	2.74	Ipp	16351		2.25
Dtl	76843	4.19	18.32	Acot9	56360		1.66	Lsm5	66373		1.7	Clic4	29876	2.31	2.56	Pls3	102866		2.16
Rad51	19361	2.92	15.71	Soat1	20652		1.65	Sfrs2	20382		1.65	Slc35b1	110172		2.15	Phlda3	27280		2.1
Pttg1	30939		8.1	Nup93	71805		1.62	Translation				Arl1	104303		2.07	Dsp	109620		1.96
Dna2l	327762	1.68	7.48	Kpna3	16648		1.56	Farsb	23874		4.68	Lman1	70361		1.98	Prdx1	18477		1.91
Brca1	12189	2.04	5.87	Electron transport				Mrpl27	94064	1.84	2.41	Vps54	245944		1.94	Tmem41b	233724		1.83
Smc2	14211		3.55	Nqo2	18105		3.3	Eif4e2	26987	1.52	2.04	Mtch2	56428		1.86	Rcn1	19672	1.6	1.77
Mcm2	17216	1.56	3.4	Etfb	110826		3.11	Eif1ay	66235		1.86	Snx5	69178	1.77	1.85	Esd	13885		1.73
Rfc5	72151		2.7	Pdia6	71853	1.6	2.42	Mrpl18	67681		1.69	Clcn5	12728		1.85	Psmc3ip	19183		1.71
Mcm3	17215		2.7	Gsr	14782		2.06	Eif3s1	78655		1.63	Slc2a3	20527		1.83	Ranbp1	19385		1.67
Mcm4	17217		2.59	Cyp51	13121		1.94	Mrpl16	94063		1.52	Nup62	18226		1.78	Nup85	445007		1.62
Nudt1	17766	1.66	2.53	Uqcrb	67530		1.92	Protein phosphorylation				Slc33a1	11416		1.72	Ppp1r7	66385		1.62
Orc6l	56452		2.44	Txnl1	53382		1.81	Melk	17279	4.05	17.84	Golt1b	66964		1.7	Psmd7	17463	1.84	1.54
Rfc4	106344		2.4	Sqle	20775		1.69	Bub1	12235		7.69	Slc4a7	218756		1.69	Cox4nb	18117		1.54
Rpa3	68240		2.22	Txndc4	76299		1.6	Wee1	22390	2.07	6.06	Bcap29	12033	1.61	1.65	Asah1	11886		1.53
Dtymk	21915	1.65	2.21	Txnl5	52700		1.6	Ryk	20187		5.21	Slc12a2	20496		1.57	Uck2	80914	1.74	1.52
Hat1	107435		2.15	Chromatin modification/Assembly				Plk4	20873	1.54	4.75	Inhibitorysignal/Apoptosis				Tiprl	226591		1.51
Brca2	12190		2.01	Nusap1	108907	1.86	9.22	Ttk	22137		3.62	Ckap2	80986		5.44
Blm	12144		1.97	Mad2l1	56150	1.61	6.8	Mapk6	50772		2.07	Gas2	14453		4.73
Topbp1	235559		1.96	Tmem38b	52076		2.7	Chek2	50883		2.07	Cell adhesion/Communication
Ranbp5	70572		1.72	Nek2	18005		2.45	Ppap2a	19012		2.05	Adam19	11492		4.89
Dbf4	27214		1.69	Suv39h2	64707		2.04	Pigf	18701		1.61	Adam9	11502		2.82
Ube2n	93765		1.64	Cbx1	12412		1.94	Acp1	11431		1.56	Tnc	21923	1.94	1.56
Nudt5	53893		1.52	Nap1l1	53605		1.65	Ptprk	19272		1.54	Vcl	22330		1.66
				Smarcad1	13990		1.56