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. 2010 Aug;177(2):586–597. doi: 10.2353/ajpath.2010.091217

Figure 5.

Figure 5

The CpG sites methylation status in the MKN45, BGC823, SGC7901, KATO3, AGS, RF1, and RF48 cell lines. A: Schematic representation of CpG dinucleotide distribution in 1646bp S100A6 gene and its 1000 bp upstream. B: The methylation status of the CpG sites in the P/E1 and E2/I2 regions. Each bar represents one CpG pair: black fully filled bar, cytosine residue methylated; white bar, cytosine residue unmethylated; half-filled bar: cytosine residue partially methylated. C: The different methylation status of the seventh and eighth CpG sites in the P/E1 region and the second to fifth CpG sites in the E2/I2 region. The red arrows represent the methylation positive (upper) and methylation negative (lower) CpG sites respectively.