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. 2010 Aug;177(2):865–872. doi: 10.2353/ajpath.2010.091096

Figure 7.

Figure 7

In vivo inability to repair DNA damage (CPD) in XP-C regenerated skin. A: CPD immunostaining of 4 BED-irradiated normal African-derived skin (control) section two hours after irradiation. B: CPD immunostaining of 4 BED-irradiated control skin section 72 hours after irradiation. C: CPD immunostaining of 4 BED-irradiated XP-C regenerated skin section 2 hours after irradiation. D: CPD immunostaining of 4 BED-irradiated XP-C regenerated skin section 72 hours after irradiation. Note the persistence of CPD-labeled cells in all epidermal strata indicating a DNA damage repair defect. Dotted lines depict the epidermal-dermal border. Scale bar = 50 μm.