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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Neurobiol Dis. 2010 May 20;39(3):409–422. doi: 10.1016/j.nbd.2010.05.013

Figure 4. Immunization with SDPM1 prior to plaque onset improves cognitive performance in Morris water maze tests.

Figure 4

Young (beginning at 5 mo and ending at 12 mo, A–C) or Old (beginning at 12mo and ending at 18 mo, D–F) Mock-, SDPM1-, and SDPM2-immunized APPswePSEN1(A246E) (APP/PS1) mice were compared to non-immunized wild type (WT) animals in the Morris water maze test for escape latency (A. D), probe test (B, E) and swim speed (C, F). Errors are SEM for n=7–12 animals per condition with n=4 measurements per animal per condition.