Table 7.
| Table 7a. Overall Survival - Group 1 (PTV2< 75 cc) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Month | 66 Gy | 72 Gy | 78 Gy | 84 Gy | ||||
| Survival (%) (95% C.I.) |
# at Risk |
Survival (%) (95% C.I.) |
# at Risk |
Survival (%) (95% C.I.) |
# at Risk |
Survival (%) (95% C.I.) |
# at Risk |
|
| 0 | 100 | 22* | 100 | 23 | 100 | 27 | 100 | 22 |
| 3 | 95 (72,99) |
21 | 87 (65,96) |
20 | 96 (76,99) |
26 | 91 (68,98) |
20 |
| 6 | 86 (63,95) |
19 | 83 (60,93) |
19 | 93 (74,98) |
25 | 82 (59,93) |
18 |
| 9 | 77 (54,90) |
17 | 70 (47,84) |
16 | 63 (42,78) |
17 | 73 (49,87) |
16 |
| 12 | 45 (24,64) |
10 | 48 (27,66) |
11 | 48 (29,65) |
13 | 73 (49,87) |
16 |
| 18 | 27 (11,46) |
6 | 43 (23,62) |
10 | 30 (14,47) |
8 | 55 (32,72) |
12 |
| 24 | 27 (11,46) |
6 | 26 (11,45) |
6 | 11 (3,26) |
3 | 41 (21,60) |
8 |
| 30 | 23 (8,41) |
5 | 22 (8,40) |
5 | 4 (0.3,16) |
1 | 24 (8,44) |
4 |
| 36 | 18 (6,36) |
4 | 17 (5,35) |
4 | -- | 0 | 24 (8,44) |
2 |
| MST (months) | 11.6 | 11.8 | 11.8 | 19.3 | ||||
| Dead/Total | 20/22 | 20/23 | 26/27 | 16/22 | ||||
| Median Follow- up Time (range) |
11.6(1.7–70.2) | 11.8(0.6–71.9) | 11.8(1.5–34.7) | 19.3 (1.8–48.2) | ||||
| Table 7b. Overall Survival - Group 2 (PTV2 ≥ 75 cc) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Month | 66 Gy | 72 Gy | 78 Gy | 84 Gy | ||||
| Survival (%) (95% C.I.) |
# at Risk |
Survival (%) (95% C.I.) |
# at Risk |
Survival (%) (95% C.I.) |
# at Risk |
Survival (%) (95% C.I.) |
# at Risk |
|
| 0 | 100 | 33 | 100 | 23 | 100 | 35 | 100 | 18 |
| 3 | 94 (78,98) |
31 | 83 (60,93) |
19 | 94 (79,99) |
33 | 78 (51,91) |
14 |
| 6 | 67 (48,80) |
22 | 65 (42,81) |
15 | 83 (66,92) |
29 | 78 (51,91) |
14 |
| 9 | 39 (23,55) |
13 | 61 (38, 77) |
14 | 69 (50,81) |
24 | 61 (35,79) |
11 |
| 12 | 30 (16,46) |
10 | 52 (31,70) |
12 | 46 (29,61) |
16 | 56 (31,75) |
10 |
| 18 | 18 (7,33) |
6 | 13 (3,30) |
3 | 20 (9, 34) |
7 | 39 (17,60) |
7 |
| 24 | 9 (2,22) |
3 | 9 (11,45) |
2 | 11 (4,24) |
4 | 28 (10,49) |
5 |
| 30 | 6 (1,18) |
2 | 4 (0.3,18) |
1 | 6 (1,17) |
2 | 17 (4,37) |
3 |
| 36 | 6 (1,18) |
2 | 4 (0.3,18) |
1 | 6 (1,17) |
2 | 6 (0.4,22) |
1 |
| MST (months) | 8.2 | 12.3 | 10.0 | 13.9 | ||||
| Dead/Total | 31/33 | 23/23 | 34/35 | 18/18 | ||||
| Median Follow- up Time (range) |
8.2 (0.9–79.4) | 12.3 (0.3–71.4) | 10.0 (0.8–49.0) | 13.9 (1.2–43.6) | ||||
*
One patient died between randomization and RT start after day 1 of the first chemotherapy cycle. C.I., confidence interval
C.I., confidence interval