Table 2. Mean Cocaine ED50 Values in mg/kg (95% CL) Under Baseline Conditions, During 7-day Access to Supplemental Cocaine Self-Administration Sessions 7.5 min Post-Injection Time-Outs, and on Days 1, 4, and 7 After Termination of Access to Supplemental Sessions +7 Days of Cocaine Abstinence.

Condition	Cocaine ED50 in mg/kg (95% CL)
Baseline	0.018 (0.018–0.018)
During access	0.023 (0.011–0.047)
Post abstinence day 1	0.017 (0.015–0.019)
Post abstinence day 4	0.018 (0.018–0.018)
Post abstinence day 7	0.026 (0.013–0.055)

Cocaine ED50 values were not significantly different from baseline either during extended cocaine access or after the 7-day abstinence period.