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Antiretrovirals currently in phase II/III of clinical development
| Drug | Mechanism | Activity against PI and RT resistant strains | |
|---|---|---|---|
| Maraviroc | MVC | CCR5 inhibitor | Yes, but not X4 variants |
| Vicriviroc | SCH D | Yes, but not X4 variants | |
| Etravirine | TMC-125 | Non-nucleoside reverse transcriptase inhibitor | Yes, also NNRTI-resistant strains |
| TMC-278 | Yes, also NNRTI-resistant strains | ||
| n/a | MK-0518 | Integrase strand transfer inhibitor | Yes |
| n/a | GS-9137 | Yes |
