Table 3.
Variables: | N | Relative Risk of relapse/progression or death (95% CI) |
P-value |
---|---|---|---|
Main effect: | |||
No rituximab | 812 | 1.00 | |
Rituximab | 174 | 0.64 (0.50 – 0.81) | <0.001 |
Other significant covariates: | |||
Age at transplant, years | |||
<55 | 562 | 1.00 | |
≥ 55 | 424 | 1.45 (1.23 – 1.71) | <0.001 |
Disease status at transplant | |||
(1) CR1 | 167 | 1.00 | <0.001a |
(2) PIF-sensitive | 182 | 1.24 (0.91 – 1.69) | 0.18 |
(3) PIF-resistant | 54 | 3.38 (2.30 – 4.96) | <0.001 |
(4) REL-sensitive | 298 | 2.02 (1.53 – 2.67) | <0.001 |
(5) REL-resistant | 69 | 2.65 (1.83 – 3.82) | <0.001 |
(6) CR2+ | 158 | 1.57 (1.14 – 2.14) | 0.010 |
(7) Unknown | 58 | 2.13 (1.45 – 3.15) | 0.001 |
Number of lines of chemotherapy | |||
≤2 | 561 | 1.00 | <0.001b |
>2 | 418 | 1.61 (1.36 – 1.91) | <0.001 |
Abbreviations: CI = confidence interval.
Cox models stratified on karnofsky performance score
Six degrees of freedom
Two degrees of freedom