Table 4.
Variables: | N | Relative Risk of death (95% CI) |
P-value |
---|---|---|---|
Main effect: | |||
No rituximab | 818 | 1.00 | |
Rituximab | 176 | 0.74 (0.56 – 0.99) | 0.039 |
Other significant covariates: | |||
Age at transplant, years | |||
<55 | 568 | 1.00 | |
≥ 55 | 426 | 1.53 (1.29 – 1.83) | <0.001 |
Disease status at transplant | |||
(1) CR1 | 168 | 1.00 | <0.001a |
(2) PIF-sensitive | 184 | 1.29 (0.91 – 1.82) | 0.15 |
(3) PIF-resistant | 54 | 3.23 (2.14 – 4.87) | <0.001 |
(4) REL-sensitive | 301 | 2.06 (1.51 – 2.81) | <0.001 |
(5) REL-resistant | 69 | 2.57 (1.73 – 3.83) | <0.001 |
(6) CR2+ | 159 | 1.58 (1.12 – 2.24) | 0.010 |
(7) Unknown | 59 | 2.27 (1.50 – 3.44) | <0.001 |
Number of lines of chemotherapy | |||
≤2 | 564 | 1.00 | <0.001b |
>2 | 422 | 1.53 (1.28 – 1.82) | <0.001 |
Year of transplant | |||
1996–1999 | 735 | 1.00 | |
2000–2003 | 259 | 0.73 (0.57 – 0.94) | 0.013 |
Abbreviations: CI = confidence interval.
Cox models stratified on karnofsky performance score
Six degrees of freedom
Two degrees of freedom