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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Nov;15(11):1455–1464. doi: 10.1016/j.bbmt.2009.07.017

Table 4.

Multivariate analyses for OS*

Variables: N Relative Risk
of death
(95% CI)
P-value
Main effect:
    No rituximab 818 1.00
    Rituximab 176 0.74 (0.56 – 0.99) 0.039
Other significant covariates:
Age at transplant, years
    <55 568 1.00
    ≥ 55 426 1.53 (1.29 – 1.83) <0.001
Disease status at transplant
    (1) CR1 168 1.00 <0.001a
    (2) PIF-sensitive 184 1.29 (0.91 – 1.82) 0.15
    (3) PIF-resistant 54 3.23 (2.14 – 4.87) <0.001
    (4) REL-sensitive 301 2.06 (1.51 – 2.81) <0.001
    (5) REL-resistant 69 2.57 (1.73 – 3.83) <0.001
    (6) CR2+ 159 1.58 (1.12 – 2.24) 0.010
    (7) Unknown 59 2.27 (1.50 – 3.44) <0.001
Number of lines of chemotherapy
    ≤2 564 1.00 <0.001b
    >2 422 1.53 (1.28 – 1.82) <0.001
Year of transplant
    1996–1999 735 1.00
    2000–2003 259 0.73 (0.57 – 0.94) 0.013

Abbreviations: CI = confidence interval.

*

Cox models stratified on karnofsky performance score

a

Six degrees of freedom

b

Two degrees of freedom