Table 3.
Paired t-test analyses of lipid values for twin pairs discordant for dementia.
Variable | N pairs | Mean Difference untransformed | Mean Difference log transformed | t | p |
---|---|---|---|---|---|
HDL | 17 | 0.024 | 0.009 | 0.176 | 0.863 |
ApoA1 | 21 | 0.030 | --- | 0.566 | 0.578 |
ApoB | 21 | 0.103 | 0.078 | 2.362 | 0.028 |
ApoB/ApoA1 | 21 | 0.069 | 0.069 | 1.692 | 0.106 |
Triglycerides | 21 | 0.067 | 0.017 | 0.164 | 0.871 |
Total cholesterol | 21 | 0.395 | --- | 2.363 | 0.028 |
Note. log = natural log of values. T-tests for differences between log transformed variables shown where transformation applied. The lipids values for the unaffected twin were subtracted from their affected cotwin where positive differences indicate higher lipid values associated with dementia status.