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. Author manuscript; available in PMC: 2010 Aug 2.
Published in final edited form as: J Am Geriatr Soc. 2009 Feb 24;57(4):641–646. doi: 10.1111/j.1532-5415.2009.02169.x

Table 1.

Distribution of Variables at Baseline and Outcomes in All Subjects and Subjects Divided into Three CRP Groups

Variable C-reactive Protein (CRP) Levels
Undetectable Detectable Elevated
All subjects
< 0.5 mg/dL
0.5-0.7 mg/dL
≥ 0.8 mg/dL
N = 227 N = 80 N = 81 N = 66
% (#) % % % p-value
Demographics
 Female 62 (141) 61 65 59 0.719
 Have APOE4 allele 20 (45) 21 23 14 0.307
Education level
 ≤ High school graduate 26 (59) 20 27 32 0.060
 Some college to college
graduate
49 (111) 44 54 49
 Post-graduate education 25 (57) 36 19 19
Lifestyle
 Smoke 1 (3) 3 1 0 0.411
 Drink alcohol 67 (152) 69 69 62 0.739
 Use estrogen (women only) 6 (14) 4 9 6 0.422
Medical history
0.041
 Hypertension 51 (116) 40 57 59 *
0.001
 Coronary Artery Disease 14 (32) 12 25 5 *
 Myocardial Infaction 14 (31) 14 11 17 0.639
 Atrial fibrillation/arrythmias 29 (66) 24 31 35 0.378
 Heart Valve Disease 6 (14) 5 9 5 0.517
 Congestive Heart Failure 8 (18) 4 9 12 0.190
 Stroke 7 (17) 10 7 5 0.447
 Transient Ischemic Attack 15 (33) 13 12 22 0.203
 High Cholesterol 29 (66) 26 34 30 0.534
 Diabetes 4 (10) 4 6 3 0.618
 Rheumatoid Arthritis 8 (18) 11 4 11 0.202
 Osteoarthritis 41 (88) 41 42 40 0.982
Cognitive diagnosis
 Normal 56 (127) 54 57 58 0.882
 CIND 44 (100) 46 43 42
Outcomes
 All-cause Dementia 36 (82) 39 32 38 0.639
 All-cause Mortality 48 (108) 38 53 53 0.081
*

p < 0.05 level

APOE4 = apolipoprotein E4; CIND = Cognitively Impaired Not Demented