. Author manuscript; available in PMC: 2010 Aug 2.

Published in final edited form as: Curr Med Chem Immunol Endocr Metab Agents. 2004 Dec;4(4):349–369. doi: 10.2174/1568013043357338

Table 1.

The Water Exchange Rates, Relaxivities and Thermodynamic Stability Constants of the Four Longest Serving Contrast Agents

Complex	τ_M²⁹⁸/ns	R₁^(a)/mM⁻¹s⁻¹	log K_GdL
GdDTPA²⁻	303^(b)	4.3^(c)	22.5^(d)
GdDOTA⁻	244^(b)	4.2^(c)	24.7^(e)
GdHP-DO3A	-	3.7^(f,^g)	23.8^(h)
GdDTPA-BMA	2222^(b)	4.4^(b)	16.9⁽ⁱ⁾

^a)

Measured at 20 MHz and 25 °C

^b)

reference [17]

^c)

reference [18]

^d)

reference [19]

^e)

reference [20]

^f)

Measured at 20 MHz and 40 °C

^g)

reference [21]

^h)

reference [22]

ⁱ⁾

reference [23]