Table I.

Permeability of membranes ± adherent cells to (A) HA and (B) PRG4, calculated from lubricant transport studies.

	Permeability (10−8 cm/s)
	50 nm		90 nm		170 nm		3 μ;m
	− Cells	+ Cells	− Cells	+ Cells	− Cells	+ Cells	− Cells	+ Cells
(A) HA
MW (kDa)
Total HA	19.6 ± 6.9	4.8 ± 0.6	34.5 ± 1.1	18.5 ± 2.5	105.5 ± 31.7	42.5 ± 24.4	150.4 ± 14.2	126.5 ± 8.3
4,000	6.4 ± 3.0	0.4 ± 0.2	11.6 ± 2.0	3.1 ± 1.4	45.0 ± 24.8	31.6 ± 29.7	113.6 ± 11.2	93.1 ± 11.1
2,400	10.6 ± 5.2	0.5 ± 0.3	21.7 ± 1.9	5.9 ± 2.2	58.1 ± 19.3	38.0 ± 32.7	132.6 ± 11.5	113.4 ± 9.1
1,156	16.1 ± 8.1	0.7 ± 0.3	33.3 ± 1.7	12.7 ± 3.0	73.5 ± 14.6	45.4 ± 31.7	142.3 ± 13.6	127.6 ± 8.3
450	31.3 ± 15.4	2.3 ± 0.5	68.3 ± 3.7	41.7 ± 7.1	114.0 ± 14.8	70.7 ± 24.7	181.8 ± 19.9	163.1 ± 12.3
262	55.1 ± 23.9	9.2 ± 2.4	106.3 ± 2.7	82.4 ± 14.8	169.8 ± 22.2	114.0 ± 27.0	238.8 ± 32.5	208.7 ± 15.3
160	71.2 ± 26.1	18.8 ± 2.5	128.4 ± 2.9	94.6 ± 15.1	184.3 ± 17.4	131.7 ± 24.3	237.2 ± 30.5	224.1 ± 20.4
30	447.6 ± 28.8	170.2 ± 22.3	358.9 ± 70.7	317.5 ± 109.2	399.4 ± 46.9	389.8 ± 59.1	447.4 ± 62.7	449.6 ± 48.2
(B) PRG4	3.9 ± 1.8	3.3 ± 1.4	63.8 ± 39.5	31.7 ± 12.4	149.4 ± 28.1	137.8 ± 51.8	305.1 ± 29.8	366.4 ± 68.9